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Alternatives for Dermal Toxicity Testing

Name: Alternatives for Dermal Toxicity Testing
Brand: Springer International Publishing AG
SKU: 15362950
Price: 178.49 EUR
Availability: InStock
Author: Chantra Eskes
ISBN: 9783319503516

Chantra Eskes

Erwin van Vliet

Howard I. Maibach

Lingua

Inglese

Libro Rigido

Codice Libristo: 15362950

Casa editrice Springer International Publishing AG, agosto 2017

This book provides comprehensive information on the alternative (non-animal) dermal toxicity test me... Descrizione completa

Codice Libristo: 15362950

437 b

178.49 €

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This book provides comprehensive information on the alternative (non-animal) dermal toxicity test methods currently available for industrial, regulatory, and academic use and also explores potential future developments. It encompasses all areas of dermal toxicity, including skin irritation, skin corrosion, skin sensitization, UV-induced effects, and skin genotoxicity. An individual chapter is devoted to each test method, with coverage of the scientific basis, validation status and regulatory acceptance, applications and limitations, available protocols, and potential role within testing strategies. In addition, perspectives from the test developer are presented, for example regarding critical steps in the protocol. The closing section addresses areas that may be of relevance for the future of dermal toxicity safety testing, including the validation and regulatory acceptance of integrated testing strategies, novel complex skin models, and high-throughput screening techniques.