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Applied Pharmacometrics
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572 b
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As the title suggests this book will focus on the application of pharmacometrics in the drug development process. It begins on the conceptual level, examining pharmacometrics and pharmacodynamics in specific patient populations such as those with increasing impact on population health - such as geriatrics and the obese - but also those patient groups that are key considerations in making applications for drug approval, notably those with renal or hepatic impairment. Pharmacometrics also plays a key role in personalized medicine, the selection of the right drug, right dose for an individual patient and diagnosis. The book will also explore multiple case examples of the use of pharmacometrics in specific disease states, including diabetes, oncology, infectious diseases and cardiovascular disease. In addition, this real world translation of theory into practice, the knowledge of the application in major organ systems, has impact in the successful development of drugs for other conditions, pyschiatric disorders, Alzheimers disease and pain.
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