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Bradykinin: From Vasodilation to Neuroinflammation is a complete guide to this multi-functional peptide, and its impact across the human body. Early chapters provide an overview of the biosynthesis and metabolism of bradykinin, understanding of its receptors and signaling pathways, and the therapeutic value of agonists and antagonists for targeting these. Bradykinin: From Vasodilation to Neuroinflammation explores the role of bradykinin in vascular, renal and brain function, as well as influence on various conditions and diseases, including inflammation, pain, cardiovascular disease, renal disease, obesity, ischemic stroke, and infectious disease, including Covid-19. This is a volume in the Molecular Mediators in Health and Disease series. This book includes extensive coverage of bradykinin biochemistry and molecular biology, as well as therapeutic potential of bradykinin, and is an ideal reference for researchers working across these fields.
- Explores the communication role of bradykinin in both homeostasis and pathologic states
- Investigates bradykinin across various conditions, including cardiovascular and renal disease, heart failure, diabetes and cancer
- Discusses bradykinin receptors and their signalling pathways
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