Concepts and Methodology in Cancer Diagnostics

Concepts and Methodology in Cancer Diagnostics: An Immunological, Biochemical and Molecular Approach provides an exclusive combination of all basics and recent techniques, methodology, and advancements in the field of cancer diagnostics. With a strong focus on the procedures and techniques involved in cancer diagnostics, content also gives insight into the molecular tests required for different tumors for the administration of targeted drugs and precision medicine. In 11 chapters Concepts and Methodology in Cancer diagnostics: An Immunological, Biochemical and Molecular Approach introduces the methods and technologies based on DNA and RNA based biomarkers, biochemical and immunological markers, genetic signatures, epigenetic changes and exosomes in blood, and tissue and body fluids. There is also additional focus on specific mutations and expression markers that are utilized for the diagnosis of cancers of unknown primary origin (CUPs). Concepts and Methodology in Cancer Diagnostics: An Immunological, Biochemical and Molecular Approach presents a compilation of imperative topics and includes lists of the necessary materials and reagents needed, step-by-step instructions, readily reproducible laboratory protocols, as well as tips on troubleshooting and known pitfalls. This book is a valuable resource for medical professionals and researchers to understand the concepts of validated protocols and methodology in diagnosing cancer, its prognosis, and predictive value. • Discusses and provides solution for quality control procedures in antibody tests in cancer diagnostics.• Gives insights into the limitations and biasness of biomarker testing specifically immunohistochemical and molecular markers.• Provides procedures and addresses the challenges related to quality control, proficiency testing, accuracy, and precision of biomarker testing in cancer• Explores numerous methods used in basic and diagnostic laboratories to characterize cancer-related biomarkers, including cancer risk assessment, diagnosis, and determination of cancer progression.