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Copper Complexes - Vol II

Name: Copper Complexes - Vol II
Brand: LAP Lambert Academic Publishing
SKU: 12628474
Price: 37.29 EUR
Availability: InStock
Author: Richa Kothari
ISBN: 9783659880575

Synthesis, Characterization and Biological Evaluation of NNS donor schiff base molecular adducts of Copper (II) Chloride

Richa Kothari

Lingua

Inglese

Libro In brossura

Codice Libristo: 12628474

Casa editrice LAP Lambert Academic Publishing, novembre 2015

NNS Schiff base molecular adducts belong to a group of thiourea derivatives and the biological activ... Descrizione completa

Codice Libristo: 12628474

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37.29 €

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NNS Schiff base molecular adducts belong to a group of thiourea derivatives and the biological activities of which are a function of the parent aldehyde or ketone are the most important properties of thiosemicarbazone class of ligands (hydrazine carbothioamindes). Their metal complexes, especially those containing copper (II) and iron (III) are more active than uncoordinated NNS Schiff base molecular adducts and enhanced biological activity of metal thiosemicarbazones has been under investigation for some time. NNS Schiff base molecular adducts are very good ligands and it has been shown that their biological activity is related to their ability to coordinate to metal centres in enzymes. NNS Schiff base molecular adducts are more active in cell destruction, as well as in the inhibition of DNA synthesis. NNS Schiff base molecular adducts are obtained by condensation of thiosemicarbazide or a substituted thiosemicarbazide at the N (4) position with a suitable aldehyde or ketone.