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Genetic Engineering of Mesenchymal Stem Cells

Name: Genetic Engineering of Mesenchymal Stem Cells
Brand: Springer-Verlag New York Inc.
SKU: 01416371
Price: 178.69 EUR
Availability: InStock
Author: J. A. Nolta
ISBN: 9781402039355

J. A. Nolta

Lingua

Inglese

Libro Rigido

Codice Libristo: 01416371

Casa editrice Springer-Verlag New York Inc., febbraio 2006

MSC (mesenchymal stem cells) have been reported to initiate revascularization after injury, to facil... Descrizione completa

Codice Libristo: 01416371

437 b

178.69 €

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MSC (mesenchymal stem cells) have been reported to initiate revascularization after injury, to facilitate engraftment of blood-forming stem cells, and to reduce the incidence of graft-vs. host disease through their immune-suppressive qualities. Finally, bone marrow-derived MSC have been reported to home to areas of solid tumor revascularization, and thus may be used as delivery vehicles to target ablative agents into dividing tumor cells. Recently the characteristics of human MSC from adipose (fat) tissue have also been identified. The possibility of repairing tissues, speeding stem cell engraftment, and targeting solid tumors for specific killing, using MSC easily harvested from bone marrow, or better yet, from unwanted fat tissue, holds broad appeal, and is an intriguing possibility that could have dramatic effect on health care.This book has information on how to isolate, grow, and characterize MSC from marrow and fat, and gives important insight into how these cells may be used for gene delivery and cellular therapies in the future. Updates on emerging clinical trials are given.