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Genetics of Complex Human Diseases

Name: Genetics of Complex Human Diseases
Brand: Cold Spring Harbor Laboratory Press,U.S.
SKU: 04752729
Price: 84.29 EUR
Availability: InStock
Author: Ammar Al-Chalabi
ISBN: 9780879698836

Ammar Al-Chalabi

Lingua

Inglese

Libro In brossura

Codice Libristo: 04752729

Casa editrice Cold Spring Harbor Laboratory Press,U.S., settembre 2009

Many human diseases including Alzheimer's disease, schizophrenia, cancer, and cardiovascular disease... Descrizione completa

Codice Libristo: 04752729

206 b

84.29 €

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Many human diseases including Alzheimer's disease, schizophrenia, cancer, and cardiovascular disease have complex genetics that require sophisticated analysis. Genetics of Complex Human Diseases: A Laboratory Manual brings together the tools that geneticists use to find disease genes with the genetic concepts and statistical theories that underpin these research approaches. Topics covered include basic genetics and Mendelian inheritance, statistical methods, genetic epidemiology, linkage studies, transmission disequilibrium test analysis, variance components analysis, genome-wide association studies, copy-number variation, methods for high-throughput genotyping, the complexity of RNA editing, and genetic computer programs. The book's chapters, written by leading investigators in the field, blend practical information and reviews of each topic, providing both the how and the why of complex disease analysis. Genetics of Complex Human Diseases is an important guide for anyone with an interest in human genetics or who uses genetic techniques in the study of diseases with complex inheritance.