Genomics-Driven Healthcare

Trends arising in "-Omics" sciences are evaluated in terms of their current and potential future application to therapeutic design and understanding of disease. Chapters consider the impact of pharmacogenomics and bioinformatics on drug development, as well as trends in genomics as applied to understanding of neurodegenerative and lung disease, psychiatry and oncology. Following the genome studies released in early part of this century, the advent of the -Omics sciences (genomics and pharmacogenomics, proteomics, metabolomics, transcriptomics) has seen the expansion of a vast knowledgebase with utility in preventing and treating disease, and improving health for all. Bioinformatics and improved pharmacogenetic understanding forge a path for improved methods for drug discovery and design that better accounts for delivery and disposition across populations. While focusing primarily on trends in genomics that are impacting drug and pharmaceutical development, this book also explores how genomics applies to disease occurrence and progression and how this can be leveraged in managing disease and promoting health amongst different populations.