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Inflammatory Disorders

Name: Inflammatory Disorders
Brand: Springer International Publishing AG
SKU: 05153417
Price: 113.19 EUR
Availability: InStock
Author: Mieczyslaw Pokorski
ISBN: 9783319100111

Mieczyslaw Pokorski

Lingua

Inglese

Libro Rigido

Codice Libristo: 05153417

Casa editrice Springer International Publishing AG, novembre 2014

The mechanistic basis of chronic inflammation remains unclear. The research sheds new light on the i... Descrizione completa

Codice Libristo: 05153417

277 b

113.19 €

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The mechanistic basis of chronic inflammation remains unclear. The research sheds new light on the immune cells expressing the activation markers HLA-DR and regulatory T cells (Tregs) and the cells expressing Siglec receptors as being key players in the immune system responsiveness to antigens and thus in lung tissue damage of chronic inflammation. The results help understand the mechanisms of action of common drugs used in COPD, such as formoterol, tiotropium, or corticosteroids, and point to novel drug targets. The chapters also deal with brain damaging effects, by far unrecognized, of inhaled corticosteroid therapy, a time-proven management of chronic inflammatory airway conditions; asthma being a case in point. Novel methods, likely less producing side effects, of macrolide antibiotics administration by inhalation are discussed, emphasizing not only bacteriostatic but also anti-inflammatory action.