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This work is focused on the application of fundamental procedures in biology and physical/ engineering sciences aiming at the development of a marketable biotechnology. As a commodity whose process is of low added value, based on locally available feedstocks and low technology, which is produced in bulk, baker's yeast is an appropriate commodity for production in developing countries. In fact, it is produced in most developing countries and has been produced in Egypt, as a marketable commodity, for probably the last 100 years. However, again because of its low added value, the process must be highly optimized so that it is run on the most austere economic basis. Thus, the process depends on cutting cost in every step, including the lowest cost sugar substrate, the highest conversion rate for the substrates to biomass, the shortest process time, the least expensive down -stream processing, the minimum use of energy even in sterilization and cooling etc. Using a mathematical model which describes all physiological, chemical, biological and phenomenon states is the first step in that direction.
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