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Model Selection Techniques for Locating Quantitative Trait Loci

Name: Model Selection Techniques for Locating Quantitative Trait Loci
Brand: Sudwestdeutscher Verlag Fur Hochschulschriften AG
SKU: 06883303
Price: 55.89 EUR
Availability: InStock
Author: Andreas Baierl
ISBN: 9783838101224

Modifying the Bayesian Information Criterion for Locating Multiple Quantitative Trait Loci in Experimental Crosses

Andreas Baierl

Lingua

Inglese

Libro In brossura

Codice Libristo: 06883303

Casa editrice Sudwestdeutscher Verlag Fur Hochschulschriften AG, novembre 2008

Recent technological advances in genetics pose new§challenging problems to statistical methodology.... Descrizione completa

Codice Libristo: 06883303

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55.89 €

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Recent technological advances in genetics pose new§challenging problems to statistical methodology. The§genetic technique of QTL mapping deals with locating§genes that influence a quantitative character of an§organism. Within the statistical framework of model§selection, existing approaches are adapted and§modifed: The search for genetic effects is extended§to interactions between genes (i.e. epistatsis),§while taking computational performance into account.§Robust statistical methods are included in order to§cope with quantitative effects that have heavy-tailed§distribution or outliers. The performance and§applicability of all methods is assessed by extensive§simulation studies and the reanalysis of previously§published genetic data sets.