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Type 2 diabetes mellitus is a polygenic and multifactorial disorder resulting from the interaction between a genetic predisposition, environmental risk factors and behavioral patterns. It comprises a series of dysfunctions resulting from the combination of resistance to insulin action to inadequate insulin secretion. The incidence of type 2 diabetes mellitus is increasing worldwide and the prevalence of diabetes for all age-groups worldwide was estimated to be 2.8% in 2000.The number of people with diabetes is increasing due to population growth, aging, increasing prevalence of obesity physical inactivity and urbanization. The difference in the prevalence of diabetes in urban and rural indicates a major role of urbanization in the occurrence of the type 2 diabetes.Adults with diabetes mellitus also frequently develop micro and macro vascular complications which include neuropathy, nephropathy, cerebrovascular, cardiovascular diseases etc.There is an enhanced risk of coronary heart disease morbidity and mortality in type 2 diabetic patients.
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