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Stem cell therapy: An emerging modality in glomerular diseases

Name: Stem cell therapy: An emerging modality in glomerular diseases
Brand: Editions universitaires europeennes EUE
SKU: 16420825
Price: 27.99 EUR
Availability: InStock
Author: Umang Gunvantray Thakkar
ISBN: 9783330869264

Umang Gunvantray Thakkar

Lingua

Francese

Libro In brossura

Codice Libristo: 16420825

Casa editrice Editions universitaires europeennes EUE, giugno 2017

In the human body kidney is one special organ which is highly terminally differentiated and has very... Descrizione completa

Codice Libristo: 16420825

69 b

27.99 €

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In the human body kidney is one special organ which is highly terminally differentiated and has very limited capacity to regenerate following injury/ insult. Hence once glomerular diseases set in, they usually progress to end-stage renal disease (ESRD) requiring dialysis or renal transplantation (RT) for better quality of life. However shortage of implantable kidneys and complications of transplantation like immune rejection immunosuppression related morbidity/ mortality, including immunocompromised status, metabolic disorders, infections and malignancies, RT remains a challenge. Therapeutic options available for management of glomerular diseases include symptomatic treatment strategies to delay progression to ESRD. Stem cell-based therapy (SCT) forms recent innovative therapeutic modalities for such diseases due to its ability to inhibit inflammation, replenish dying tissues/ cells and promote regeneration. This review focuses on SCT for treatment of glomerular diseases, including various cell sources used and recent advances in preclinical and clinical studies.