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Targeted Protein Degradation

Name: Targeted Protein Degradation
Brand: Springer US
SKU: 35540254
Price: 188.09 EUR
Availability: InStock
Author: Christopher Hickey
ISBN: 9781071616642

Christopher Hickey

Miklos Bekes

Lingua

Inglese

Libro Rigido

Codice Libristo: 35540254

Casa editrice Springer US, agosto 2021

This volume contains a collection of innovative techniques for studying targeted protein degradation... Descrizione completa

Codice Libristo: 35540254

460 b

188.09 €

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This volume contains a collection of innovative techniques for studying targeted protein degradation. Chapters guide readers through heterobifunctional proteolysis-targeting chimeras (PROTACs) approaches, E3 ligase, E3 ligase-induced ubiquitylation, proteomic approaches, novel degrader molecules, molecular glue, and stabilize binding interaction between a target and E3 ubiquitin ligase. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Targeted Protein Degradation: Methods and Protocols aims to ensure successful results in this emerging field of drug discovery.